Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development.
The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others.
Presents revised and updated information for each chapter on systemsContains expanded sections on applied toxicologic pathologyIncludes the essential information necessary to understand toxicologic pathology in an accessible languageReview“The editors have succeeded in producing a very readable, basic textbook of current toxicologic pathology…The book provides many high quality, well labeled reproductions of light and electron micrographs…This book will be an excellent resource for graduate students in toxicology, pathology, and environmental health studies. It provides a thorough organ system based overview of current knowledge and fundamental principles of toxicologic pathology, devoid of the detailed treatment of descriptive morphology and mechanisms provided in reference texts.”–CHOICE“…a very valuable toxicopathological reference source…”–A.A. Seawright in AUSTRALIAN VETERINARY JOURNAL –This text refers to an out of print or unavailable edition of this title.
Contents فهرست فصول:۱ An Overview of Toxicologic Pathology۲ Biochemical and Molecular Basis of Toxicity۳ Pharmacokinetics and Toxicokinetics۴ Principles of Pharmacodynamics and Toxicodynamics۵ Morphologic Manifestations of Toxic Cell Injury۶ Carcinogenesis: Manifestation and Mechanisms۷ Design of Studies and Risk Management in Toxicologic Pathology: Addressing Risks in Product Discovery and Development۸ Liver and Gall Bladder۹ Cardiovascular System۱۰ Skeletal Muscle System۱۱ Urinary System۱۲ Immune System۱۳ Hematopoietic System۱۴ Respiratory System۱۵ Digestive System۱۶ Exocrine Pancreas۱۷ Male Reproductive System۱۸ Female Reproductive System۱۹ The Mammary Gland۲۰ Endocrine System۲۱ Nervous System۲۲ Special Senses۲۳ Bone and Joints۲۴ The Integumentary System۲۵ Embryo, Fetusr and Placenta
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