Easily accessible and clinically focused, Abeloff’s Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up.
Contents: فهرست فصول
PART I: SCIENCE AND CLINCIAL ONCOLOGYSECTION A: BIOLOGY AND CANCER1. Molecular Tools in Cancer Research2. Intracellular Signaling3. The Cellular Microenvironment and Metastases4. Control of the Cell Cycle5. The Pathophysiology of Cancer Cell Death6. Cancer Immunology7. Stem Cells, Cell Differentiation, and Cancer8. Vascular and Interstitial Biology of Tumors9. Cancer MetabolismSECTION B: GENESIS OF CANCER10. Environmental Factors11. DNA Damage Response Pathways and Cancer12. Viruses and Human Cancer13. Genetic Factors: Hereditary Cancer Predisposition Syndromes14. Genetic and Epigenetic Changes in CancerSECTION C: DIAGNOSIS OF CANCER15. Pathology, Biomarkers, and Molecular Diagnostics16. ImagingSECTION D: CLINICAL TRIALS17. Biostatistics and Bioinformatics in Clinical Trials18. Trial Design19. Structures Supporting Cancer Clinical Trials20. Oncology and Health Care PolicySECTION E: PREVENTION AND EARLY DETECTION21. Discovery and Characterization of Cancer Genetic Susceptibility Alleles22. Lifestyle and Cancer Prevention23. Cancer Screening and Early Detection24. Nicotine Dependence: Current Treatments and Future DirectionsSECTION F: TREATMENT25. Cancer Pharmacology26. Therapeutic Targeting of Cancer Cells: Era of Molecularly Targeted Agents27. Basics of Radiation Therapy28. Hematopoietic Stem Cell Transplantation29. Gene Therapy in Oncology30. Therapeutic Antibodies and Immunologic Conjugates31. Complementary and Alternative MedicinePART II: PROBLEMS COMMON TO CANCER AND THERAPYSECTION A: HEMATOLOGIC PROBLEMS AND INFACTIONS32. Disorders of Blood Cell Production in Clinical Oncology33. Diagnosis, Treatment, and Prevention of Cancer-Related Venous Thrombosis34. Infection in the Patient with CancerSECTION B: SYMPTOM MANAGEMENT35. Hypercalcemia36. Tumor Lysis Syndrome37. Cancer-Related Pain38. Cancer Cachexia39. Nausea and VomitingSECTION C: TREATMENT COMPLICATIONS40. Oral Complications41. Dermatologic Toxicities of Anticancer Therapy42. Cardiovascular Effects of Cancer Therapy43. Reproductive Complications44. Paraneoplastic Neurologic Syndromes45. Neurologic complications46. Endocrine Complications47. Pulmonary Complications of Anticancer TreatmentSECTION D: POST TREATMENT CONSIDERATIONS48. Rehabilitation of Individuals with Cancer49. Survivorship50. Second Malignant Neoplasms51. Caring for Patients at the End of LifeSECTION E: LOCAL EFFECTS OF CANCER AND ITS METASTASIS52. Acute Abdomen, Bowel Obstruction, and Fistula53. Superior Vena Cava Syndrome54. Spinal Cord Compression55. Brain Metastases and Neoplastic Meningitis56. Bone Metastases57. Lung Metastases58. Liver Metastases59. Malignancy-Related EffusionsSECTION F: SPECIAL POPULATIONS60. Cancer in the Elderly: Biology, Prevention, and Treatment61. Special Issues in Pregnancy62. Human Immunodeficiency Virus (HIV) Infection and CancerPART III: SPECIFIC MALIGNANCIESSECTION A63. Cancer of the Central Nervous SystemSECTION B64. Ocular Tumors65. Cancer of the Head and NeckSECTION C: SKIN66. Melanoma67. Nonmelanoma Skin Cancers: Basal Cell and Squamous Cell CarcinomasSECTION D: ENDOCRINE68. Cancer of the Endocrine SystemSECTION E: THORACIC69. Cancer of the Lung: Non-Small Cell Lung Cancer and Small Cell Lung Cancer70. Diseases of the Pleura and Mediastinum71. Cancer of the Esophagus and Gastroesophageal JunctionSECTION F: GASTROINTESTINAL72. Cancer of the Stomach and Gastroesophageal Junction73. Cancer of the Small Bowel74. Colon Cancer75. Cancer of the Rectum76. Cancer of the Anal Canal77. Liver and Bile Duct Cancer78. Carcinoma of the PancreasSECTION G: GENITOURINARY79. Cancer of the Kidney80. Carcinoma of the Bladder81. Prostate Cancer82. Cancer of the Penis83. Testicular CancerSECTION H: GYNECOLOGICAL84. Cancers of the Cervix, Vulva, and Vagina85. Cancer of the Endometrium86. Ovaries and Fallopian Tubes87. Gestational Trophoblastic Disease88. Cancer of the BreastSECTION I: SARCOMAS89. Sarcomas of Bone90. Sarcomas of Soft TissueSECTION J91. Carcinoma of Unknown PrimarySECTION K: PEDIATRICS92. Pediatric Solid Tumors93. Childhood Leukemia94. Childhood LymphomaSECTION L: HEMATOLOGICAL95. Acute Leukemias in Adults96. Myelodysplastic Syndromes97. Myeloproliferative Disorders98. Chronic Myeloid Leukemia99. Chronic Lymphoid Leukemias100. Hairy Cell Leukemia101. Multiple Myeloma and Related Disorders102. Hodgkin’s Lymphoma103. Non-Hodgkin Lymphoma104. Cutaneous T-Cell Lymphoma and Cutaneous B-Cell Lymphoma105. Adult T-Cell Leukemia-Lymphoma