Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. This edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.
Genetics: From Genes to Genomes represents a new approach to an undergraduate course in genetics. It reflects the way we, the authors, currently view the molecular basis of life. We integrate:
∙ Formal genetics: the rules by which genes are transmitted.∙ Molecular genetics: the structure of DNA and how it directs the structure of proteins.∙ Digital analysis and genomics: recent technologies that allow a comprehensive analysis of the entire gene set and its expression in an organism.∙ Human genetics: how genes contribute to health and diseases, including cancer.∙ The unity of life-forms: the synthesis of information from many different organisms into coherent models.∙ Molecular evolution: the molecular mechanisms by which biological systems, whole organisms, and populations have evolved and diverged.
About the AuthorDr. Janice Fischer is a Professor at The University of Texas at Austin, where she is an award-winning teacher of genetics and Director of the Biology Instructional Office. She received her Ph.D. in Biochemistry and Molecular Biology from Harvard University, and did postdoctoral research at The University of California at Berkeley and The Whitehead Institute at MIT. In her research, Dr. Fischer uses fruit flies to examine the roles of ubiquitin and endocytosis in cell signaling during development.
Contents فهرست فصول :Chapter 1 Genetics: The Study of Biological InformationChapter 2 Mendel’s Principles of HeredityChapter 3 Extensions to Mendel’s LawsChapter 4 The Chromosome Theory of InheritanceChapter 5 Linkager Recombination, and the Mapping of Genes on ChromosomesChapter 6 DNA Structurer Replication, and RecombinationChapter 7 Anatomy and Function of a Gene: Dissection Through MutationChapter 8 Gene Expression: The Flow of Information from DNA to RNA to ProteinChapter 9 Digital Analysis of DNAChapter 10 Genome AnnotationChapter 11 Analyzing Genomic VariationChapter 12 The Eukaryotic ChromosomeChapter 13 Chromosomal Rearrangements and Changes in Chromosome NumberChapter 14 Bacterial GeneticsChapter 15 Organellar InheritanceChapter 16 Gene Regulation in ProkaryotesChapter 17 Gene Regulation in EukaryotesChapter 18 Manipulating the Genomes of EukaryotesChapter 19 The Genetic Analysis of DevelopmentChapter 20 The Genetics of CancerChapter 21 Variation and Selection in PopulationsChapter 22 The Genetics of Complex Traits